C-type lectin receptors orchestrate antifungal immunity.

  title={C-type lectin receptors orchestrate antifungal immunity.},
  author={Brigitte A. Wevers and Teunis B H Geijtenbeek and Sonja I. Gringhuis},
  journal={Future microbiology},
  volume={8 7},
Fungal infections are an emerging threat for human health. A coordinated host immune response is fundamental for successful elimination of an invading fungal microbe. A panel of C-type lectin receptors expressed on antigen-presenting dendritic cells enable innate recognition of fungal cell wall carbohydrates and tailors adaptive responses via the instruction of CD4⁺ T helper cell fates. Well-balanced T helper cell type 1 and IL-17-producing T helper cell responses are crucial in antifungal… CONTINUE READING
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