C to U editing at position 32 of the anticodon loop precedes tRNA 5′ leader removal in trypanosomatids

Abstract

In all organisms, precursor tRNAs are processed into mature functional units by post-transcriptional changes. These involve 5' and 3' end trimming as well as the addition of a significant number of chemical modifications, including RNA editing. The only known example of non-organellar C to U editing of tRNAs occurs in trypanosomatids. In this system… (More)

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@inproceedings{Gaston2007CTU, title={C to U editing at position 32 of the anticodon loop precedes tRNA 5′ leader removal in trypanosomatids}, author={Kirk W. Gaston and Mary Anne T. Rubio and Jessica L. Spears and Irena Pastar and F. Nina Papavasiliou and Juan D. Alfonzo}, booktitle={Nucleic acids research}, year={2007} }