C terminus of the P2X7 receptor: treasure hunting

@article{CostaJunior2011CTO,
  title={C terminus of the P2X7 receptor: treasure hunting},
  author={Helio Miranda Costa-Junior and Fl{\'a}via Sarmento Vieira and Robson Coutinho-Silva},
  journal={Purinergic Signalling},
  year={2011},
  volume={7},
  pages={7-19}
}
P2X receptor (P2XR) is a family of the ATP-gated ion channel family and can permeabilize the plasma membrane to small cations such as potassium, sodium, and calcium, resulting in cellular depolarization. There are seven P2XR that have been described and cloned, with 45% identity in amino acid sequence. Each P2X receptors has two transmembrane domains that are separated by an extracellular loop and an intracellular N and C terminus. Unlike the other P2X receptors, the P2X7R has a larger C… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

Purinergic P2X7 receptors mediate cell death in mouse cerebellar astrocytes in culture.

The Journal of pharmacology and experimental therapeutics • 2013
View 5 Excerpts
Highly Influenced

Structural and Molecular Modeling Features of P2X Receptors

International journal of molecular sciences • 2014
View 4 Excerpts
Highly Influenced

Neuronal P2X7 Receptors Revisited: Do They Really Exist?

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2017
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 105 references

Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 2009
View 6 Excerpts
Highly Influenced

P2X7 receptor-Pannexin1 complex: pharmacology and signaling.

American journal of physiology. Cell physiology • 2008
View 9 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…