C-terminal fragment of tetanus toxin heavy chain activates Akt and MEK/ERK signalling pathways in a Trk receptor-dependent manner in cultured cortical neurons.

@article{Gil2003CterminalFO,
  title={C-terminal fragment of tetanus toxin heavy chain activates Akt and MEK/ERK signalling pathways in a Trk receptor-dependent manner in cultured cortical neurons.},
  author={Carles Gil and Imane Chaib-Oukadour and Jos{\'e} Aguilera},
  journal={The Biochemical journal},
  year={2003},
  volume={373 Pt 2},
  pages={613-20}
}
Previous publications from our group [Gil, Chaib, Pelliccioni and Aguilera (2000) FEBS Lett. 481, 177-182; Gil, Chaib, Blasi and Aguilera (2001) Biochem. J. 356, 97-103] have reported the activation, in rat brain synaptosomes, of several phosphoproteins, such as neurotrophin tyrosine kinase (Trk) A receptor, phospholipase Cgamma-1, protein kinase C (PKC) isoforms and extracellular-signal-regulated kinases 1 and 2 (ERK-1/2). In the present study, we examined, by means of phospho-specific… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 49 references

HC fragment of tetanus toxin activates protein kinase C isoforms and phosphoproteins involved in signal transduction

  • C. Gil, I. Chaib, J. Blasi, J. Aguilera
  • Biochem. J
  • 2001

Similar Papers

Loading similar papers…