C-reactive protein increases cytokine responses to Streptococcus pneumoniae through interactions with Fc gamma receptors.

Abstract

Streptococcus pneumoniae is the most common organism responsible for community acquired pneumonia and meningitis. In pneumococcal pneumonia, a strong local inflammatory cytokine response reduces the frequency of bacteremia and increases survival. The initiation of this cytokine response by innate recognition of bacterial cell wall components through TLR has… (More)

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