C-reactive protein frequently colocalizes with the terminal complement complex in the intima of early atherosclerotic lesions of human coronary arteries.

@article{Torzewski1998CreactivePF,
  title={C-reactive protein frequently colocalizes with the terminal complement complex in the intima of early atherosclerotic lesions of human coronary arteries.},
  author={Jan Torzewski and Michael Torzewski and David E. Bowyer and Margit Fr{\"o}hlich and W. K{\"o}nig and Johannes Waltenberger and Colin Fitzsimmons and V. Hombach},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1998},
  volume={18 9},
  pages={1386-92}
}
There is increasing evidence that complement activation may play a role in atherogenesis. Complement proteins have been demonstrated to be present in early atherosclerotic lesions of animals and humans, and cholesterol-induced atherosclerotic lesion formation is reduced in complement-deficient animals. Potential complement activators in atherosclerotic lesions are now a subject matter of debate. C-reactive protein (CRP) is an acute-phase protein that is involved in inflammatory processes in… CONTINUE READING

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