C-reactive protein and procalcitonin in the evaluation of the efficacy of a pneumococcal conjugate vaccine in Gambian children.

@article{Cheung2008CreactivePA,
  title={C-reactive protein and procalcitonin in the evaluation of the efficacy of a pneumococcal conjugate vaccine in Gambian children.},
  author={Yin Bun Cheung and Syed M. A. Zaman and Marja-Leena Ruopuro and Godwin Enwere and Richard A. Adegbola and Brian Greenwood and Felicity T. Cutts},
  journal={Tropical medicine & international health : TM & IH},
  year={2008},
  volume={13 5},
  pages={603-11}
}
OBJECTIVE To determine the value of C-reactive protein (CRP) and procalcitonin in the evaluation of the efficacy of a pneumococcal conjugate vaccine in Gambian children. METHODS The investigation was done as a substudy of a phase III pneumococcal conjugate vaccine trial. A pilot study (n = 120) to compare CRP and procalcitonin concentrations in children with pneumonia was undertaken, followed by a larger study of CRP concentrations (n = 1868) obtained from a subsample of children with… CONTINUE READING
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