C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro.

  title={C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro.},
  author={Vadiraja B Bhat and K. Madhava Madyastha},
  journal={Biochemical and biophysical research communications},
  volume={275 1},
C-Phycocyanin (from Spirulina platensis) effectively inhibited CCl(4)-induced lipid peroxidation in rat liver in vivo. Both native and reduced phycocyanin significantly inhibited peroxyl radical-induced lipid peroxidation in rat liver microsomes and the inhibition was concentration dependent with an IC(50) of 11.35 and 12.7 microM, respectively. The radical scavenging property of phycocyanin was established by studying its reactivity with peroxyl and hydroxyl radicals and also by competition… CONTINUE READING


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