C-peptide modifies leptin and visfatin secretion in human adipose tissue.

  title={C-peptide modifies leptin and visfatin secretion in human adipose tissue.},
  author={Sara Garc{\'i}a-Serrano and Carolina Guti{\'e}rrez-Repiso and Montserrat Gonzalo and Juan Antonio Garc{\'i}a-Arn{\'e}s and Sergio H. Diaz Valdes and Federico Soriguer and Vidal P{\'e}rez-Valero and Miguel A Alaminos-Castillo and Juan Francisco Cobos-Bravo and Francisco J. Moreno-Ruiz and Alberto Rodr{\'i}guez-Ca{\~n}ete and Francisca Rodr{\'i}guez-Pacheco and Eva Garc{\'i}a-Escobar and Eduardo Garc{\'i}a-Fuentes},
  volume={23 8},
OBJECTIVE The effects of C-peptide on adipose tissue, an organ involved in the development of obesity and insulin resistance, are not yet well known. The aim of this study was to determine whether C-peptide could be involved in the regulation of the adipocytokine synthesis in human visceral adipose tissue. METHODS The association between C-peptide and different serum adipocytokines, with an intravenous glucose tolerance test (IVGTT), and in an in vitro study in subjects without obesity and in… CONTINUE READING