C-fiber-evoked autonomic cardiovascular effects after injection of Piper betle inflorescence extracts.

  title={C-fiber-evoked autonomic cardiovascular effects after injection of Piper betle inflorescence extracts.},
  author={S J Chen and B. N. Wu and Jwu-Lai Yeh and Yi-Ching Lo and Ih-Sheng Chen and Ing Jun Chen},
  journal={Journal of ethnopharmacology},
  volume={45 3},
Cardiovascular Effects of Eugenol, a Phenolic Compound Present in Many Plant Essential Oils, in Normotensive Rats
Results show that i.v. treatment of rats with Eug induces dose-dependent hypotension and bradycardia, which occurred independently, and released nitric oxide from vascular endothelial cells seems to be not involved in the mediation of Eug-induced hypotension.
The presence of Cholinomimetic and calcium channel antagonist constituents in Piper betle Linn.
Data indicate that the plant contains cholinomimetic and possible calcium channel antagonist constituents, which are concentrated in the aqueous and ethyl acetate fractions respectively, and it is suggested that some of the traditional uses of this plant may be explained on the basis of these activities.
Study the effect of phytochemical constituents of Piper betel leaves extracts on liver disorders by in vivo model.
Piper betel leaves extract (PBLE) was able to protect the liver against the oxidative damage produced by CCl 4, and a significant reduction in serum SGOT, SGPT, ALP, ACP, lipid peroxidation and improvement in CAT, SOD, GSH, MDA level in the liver were observed when compared with CCl 3 administered rats.
Metabolic effects of the consumption of Areca catechu
Nitrosated derivatives of arecal alkaloids, proven carcinogens inducing tumours throughout the upper gut and foregut derivatives in animals, are also associated with increased tumour risks in man.
The scrutiny of present overview revealed pharmacognostical, phytochemical and some notable pharmacological activities of the plant.
A Review on Piper betle L.: Nature’s Promising Medicinal Reservoir.
Piper betle Linn. an important species of the Piperaceae family, is an evergreen and perennial creeper, with glossy heart-shaped leaves that are magnificent reservoirs of phenolic compounds with
Piper betle L.: A review on its ethnobotany, phytochemistry, pharmacological profile and profiling by new hyphenated technique DART-MS (Direct Analysis in Real Time Mass Spectrometry).
The present review summarizes the information concerning the botany, ethnopharmacology, phytochemistry, biological activity and use of hyphenated analytical technique like DART-MS (Direct Analysis in Real Time Mass Spectrometry) and other techniques for characterizing various compounds from P. betle plant.
The Effect of the Extracts of Betel (Piper betel) Leaves on the Content of IL-1? as the Inflammatory Cytokine in Experimental Mice Using an Acute Wound Healing Modeling
This study aims to determine the effect of ethyl acetate derived from the leaves extraction of betel (Piper betel) on the content of Interleukin- 1β (IL - 1β) in experimental mice using an acute


Effects of clonidine and yohimbine on a C‐fibre‐evoked blood pressure reflex in the rat
It was concluded that α2‐adrenoceptors in the spinal cord inhibit the capsaicin‐evoked depressor reflex and that pre‐ and postsynaptic α2 • adrenoception in the brain stem modulate this reflex.
Hydroxychavicol: a new anti-nitrosating phenolic compound from betel leaf.
Hydroxychavicol and eugenol exhibit dose-dependent suppression of nitrosation in vitro without affecting the survival of the bacteria.
Capsaicin-induced reflex fall in rat blood pressure is mediated by afferent substance P-containing neurones via a reflex centre in the brain stem
Using spinal rats or decerebration experiments, the centre of the capsaicin-evoked reflex fall in blood pressure could be localized in the brain stem and was exclusively mediated by substance P-containing primary afferent fibres.
Effect of Eugenol on Constrictor Responses in Blood Vessels of the Rabbit Ear
  • W. Hume
  • Biology, Medicine
    Journal of dental research
  • 1983
Eugenol appeared to act as an inhibitor of smooth muscle contractility in rabbits and depressed vasoconstrictor responses to exogenous norepinephrine, histamine, and peri-arterial sympathetic nerve stimulation in the isolated central artery of the rabbit ear.