C-cell hyperplasia. An ultrastructural analysis.

  title={C-cell hyperplasia. An ultrastructural analysis.},
  author={Ronald A DeLellis and Gretl Nunnemacher and Hubert J. Wolfe},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  volume={36 3},
The C-cell is the source of the hypocalcemic polypeptide hormone, calcitonin. Sequential increments in calcitonin response to provocative calcium and pentagastrin infusions have been used to identify family members at high risk for the development of medullary thyroid carcinoma, a neoplasm of C-cell origin. Correlative light microscopic and… CONTINUE READING