C-acylation of cyclopropanols: preparation of functionalized 1,4-diketones.


A convenient method for preparing attractively functionalized 1,4-diketones has been devised by palladium-catalyzed cross-coupling of cyclopropanols and acyl chlorides. The utility of this method has been demonstrated in an enantioselective synthesis of (+)-myrmicarin 217. 
DOI: 10.1021/ol400666x


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