C-X-C motif receptor 7 in gastrointestinal cancer.

  title={C-X-C motif receptor 7 in gastrointestinal cancer.},
  author={Hwan-Jung Yun and Hyewon Ryu and Yoon Seok Choi and Ik-Chan Song and Deog-Yeon Jo and Samyong Kim and Hyo Jin Lee},
  journal={Oncology letters},
  volume={10 3},
Chemokine receptors are key mediators of normal physiology and numerous pathological conditions, including inflammation and cancer. This receptor family is an emerging target for anticancer drug development. C-X-C motif receptor 7 (CXCR7) is an atypical chemokine receptor that was first cloned from a canine cDNA library as an orphan receptor and was initially named receptor dog cDNA 1 (RDC1). Shortly after demonstrating that RDC1 binds with its ligand, stromal cell-derived factor-1α and… CONTINUE READING
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