César Milstein, the father of modern immunology
@article{Springer2002CsarMT, title={C{\'e}sar Milstein, the father of modern immunology}, author={Timothy A. Springer}, journal={Nature Immunology}, year={2002}, volume={3}, pages={501-503} }
In memoriam: César Milstein, who with the late Georges Köhler invented monoclonal antibodies, died on 24 March 2002. Their invention sprang from basic research on antibody diversity and specificity, and spawned revolutionary advances in biology, medicine and industry.
13 Citations
Immunology south of the equator in the Americas
- Political ScienceNature Immunology
- 2008
Despite a troubled economic and political past, a tradition of fundamental research in immunology and infectious diseases has been fostered in Argentina, Brazil and Chile, as well as in other South…
infected individuals - Conservation of unique cell-surface CD antigen mosaics in HIV-1
- History
- 2013
doi:10.1182/blood-2004-12-4642Prepublished online April 12, 2005;2005 106: 1003-1007€€€€Erber, Mark Bower, Brian Gazzard, Richard I. Christopherson and Mike A. ScottStephen P. Mulligan, Larissa…
Human immunology and immunotherapy: main achievements and challenges
- BiologyCellular & molecular immunology
- 2020
Improvement in knowledge not only regarding immune-mediated illnesses and how the immune system works and interacts with other systems and components (such as the microbiome) but also in terms of ways to manipulate this system through immunotherapy is improved.
Immune response modifiers in the treatment of asthma: A PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology.
- Biology, MedicineThe Journal of allergy and clinical immunology
- 2012
Rapid and efficient preparation of monoclonal antibodies against 35 kDa lipoprotein of Mycoplasma penetrans.
- BiologyHybridoma
- 2007
The first report on the preparation of mAbs against M. penetrans that is specific to 35 kDa lipoprotein using popliteal lymph nodes is reported, which may become a method of choice for the generation and production of MAbs in a short period of time.
CD Nomenclature 2015: Human Leukocyte Differentiation Antigen Workshops as a Driving Force in Immunology
- BiologyThe Journal of Immunology
- 2015
How the CD nomenclature was established is described, the official updated list of CD molecules is presented, and a rationale for their usefulness in the 21st century is provided.
Conservation of unique cell-surface CD antigen mosaics in HIV-1-infected individuals.
- Biology, MedicineBlood
- 2005
An invariant HIV-induced CD antigen signature has been defined that is both robust and independent of clinical outcome, composed of a unique profile of CD antigen expression levels that are both increased and decreased relative to internal controls.
HIV-1-infected individuals Conservation of unique cell-surface CD antigen mosaics in
- Biology, Medicine
- 2010
This paper aims to provide a history of immunobiology in patients with documented cases of central giant cell granuloma dating back to the 1950s and 60s.
Relevance of Antibody Validation for Flow Cytometry
- BiologyCytometry. Part A : the journal of the International Society for Analytical Cytology
- 2019
It is argued that significant efforts should be invested by antibody users, developers, manufacturers, and publishers to increase the quality and reproducibility of published studies and community effort shall lead to the public availability of large data sets that can serve as a benchmark for antibody performance.
Tratamiento del asma: la terapia biológica que viene
- Philosophy
- 2016
Las tecnicas de produccion de anticuerpos monoclonales contra dianas especificas, y los procedimientos de biologia molecular que facilitan la reduccion su inmunogenicidad en sujetos humanos, han…