C/EBPbeta activates E2F-regulated genes in vivo via recruitment of the coactivator CREB-binding protein/P300.

@article{Wang2007CEBPbetaAE,
  title={C/EBPbeta activates E2F-regulated genes in vivo via recruitment of the coactivator CREB-binding protein/P300.},
  author={Haitao Wang and Brian Larris and Tanuja Harshani Peiris and Liping Zhang and John Le Lay and Yan Gao and Linda E. Greenbaum},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 34},
  pages={24679-88}
}
The E2F transcription factors play an essential role in regulating the G(1)- to S-phase transition of the cell cycle. Previous studies have identified the importance of interactions between E2Fs and other transcription factors as a mechanism for transcriptional control of a subset of E2F regulated target genes. However, the mechanisms responsible for E2F target gene specificity remain incompletely understood. Here we report that in a mammalian in vivo model of synchronized proliferation, C… CONTINUE READING

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