C/EBPalpha regulates generation of C/EBPbeta isoforms through activation of specific proteolytic cleavage.

@article{Welm1999CEBPalphaRG,
  title={C/EBPalpha regulates generation of C/EBPbeta isoforms through activation of specific proteolytic cleavage.},
  author={Alana L Welm and Nikolai A. Timchenko and Gretchen J. Darlington},
  journal={Molecular and cellular biology},
  year={1999},
  volume={19 3},
  pages={1695-704}
}
C/EBPalpha and C/EBPbeta are intronless genes that can produce several N-terminally truncated isoforms through the process of alternative translation initiation at downstream AUG codons. C/EBPbeta has been reported to produce four isoforms: full-length 38-kDa C/EBPbeta, 35-kDa LAP (liver-enriched transcriptional activator protein), 21-kDa LIP (liver-enriched transcriptional inhibitory protein), and a 14-kDa isoform. In this report, we investigated the mechanisms by which C/EBPbeta isoforms are… CONTINUE READING
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