C/EBPalpha is required for differentiation of white, but not brown, adipose tissue.

@article{Linhart2001CEBPalphaIR,
  title={C/EBPalpha is required for differentiation of white, but not brown, adipose tissue.},
  author={Heinz G. Linhart and Kazumi Ishimura-Oka and Francesco Demayo and Tetsuya Kibe and David Repka and Brian J. Poindexter and Roger J. Bick and Gretchen J. Darlington},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2001},
  volume={98 22},
  pages={12532-7}
}
The transcription factor CCAAT enhancer binding protein alpha (C/EBPalpha) is expressed at high levels in liver and adipose tissue. Cell culture studies show that C/EBPalpha is sufficient to trigger differentiation of preadipocytes into mature adipocytes, suggesting a central role for C/EBPalpha in the development of adipose tissue. C/EBPalpha knockout mice… CONTINUE READING