C/EBPα down-regulation is associated with reduced hepatic cellular viability during hypoxia in vitro and in vivo.

@article{Zhou2011CEBPDI,
  title={C/EBPα down-regulation is associated with reduced hepatic cellular viability during hypoxia in vitro and in vivo.},
  author={Qian Yun Zhou and Ding Liu and Shi Feng Huang and Yang An Wen and Peng Luo and Yu Xiang and Shan Sun and Yu Fang Dong and L. P. Zhang},
  journal={Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie},
  year={2011},
  volume={63 4},
  pages={307-10}
}
C/EBPα transcription factor is a key regulator in liver biology and was preliminarily shown to be down-regulated in hypoxic primary rat hepatocytes. The aim of this study was to explore the possible association between C/EBPα expression level and hepatocyte viability in both the in-vitro cultured hypoxic rat primary hepatocytes and two models of acute liver… CONTINUE READING