Bystin in perineural invasion of prostate cancer.

  title={Bystin in perineural invasion of prostate cancer.},
  author={Gustavo Ayala and Hong Dai and Rile Li and Michael Ittmann and Timothy C Thompson and David Rowley and Thomas M. Wheeler},
  journal={The Prostate},
  volume={66 3},
BACKGROUND Bystin, Trophinin, and Tastin are component proteins of an adhesion molecule complex that plays a crucial role in the initial attachment of the embryo to the uterus. METHODS Profiling of genes differentially expressed in the perineural invasion (PNI) in vitro model by gene microarray analysis showed overexpression of bystin in prostate cancer cells co-cultured with nerves. Validation was performed at the RNA levels using quantitative PCR. RESULTS Bystin is overexpressed in cells… CONTINUE READING


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