Bystander modulation of chemokine receptor expression on peripheral blood T lymphocytes mediated by glatiramer therapy.

@article{Allie2005BystanderMO,
  title={Bystander modulation of chemokine receptor expression on peripheral blood T lymphocytes mediated by glatiramer therapy.},
  author={Rameeza Allie and Lina Hu and Katherine Marie Mullen and Suhayl Dhib-Jalbut and Peter A. Calabresi},
  journal={Archives of neurology},
  year={2005},
  volume={62 6},
  pages={889-94}
}
BACKGROUND Glatiramer acetate therapy is thought to be effective for multiple sclerosis (MS) by promoting T(H)2 cytokine deviation, possibly in the brain, but the exact mechanism and site of action are incompletely understood. Determining the site of action and effect of glatiramer on cell trafficking is of major importance in designing rational combination therapy clinical trials. OBJECTIVE To determine whether glatiramer therapy will also act in the peripheral blood through bystander… CONTINUE READING

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