Bystander activation of CD4+ T cells accounts for herpetic ocular lesions.

@article{Gangappa2000BystanderAO,
  title={Bystander activation of CD4+ T cells accounts for herpetic ocular lesions.},
  author={S Gangappa and S P Deshpande and Barry T Rouse},
  journal={Investigative ophthalmology & visual science},
  year={2000},
  volume={41 2},
  pages={453-9}
}
  • S Gangappa, S P Deshpande, Barry T Rouse
  • Published 2000 in Investigative ophthalmology & visual science
PURPOSE Stromal keratitis is an immunopathologic consequence of herpes simplex virus (HSV) infection of the cornea. The lesion is immunopathologic, but the identities of molecules that drive the reaction remain unresolved. To exclude viral antigen recognition as a necessary step in the disease process, ocular HSV infection was followed in Tg-RAG mice (OVA… CONTINUE READING