Bypass chromatography--design and analysis of an improved strategy for operating batch chromatography processes.

@article{Siitonen2012BypassCA,
  title={Bypass chromatography--design and analysis of an improved strategy for operating batch chromatography processes.},
  author={Jani Siitonen and Tuomo Sainio and Arvind Rajendran},
  journal={Journal of chromatography. A},
  year={2012},
  volume={1230},
  pages={77-92}
}
The possibility to improve the performance of batch chromatographic separations by using so-called bypass method is analyzed for the first time. In bypass chromatography, only a part of the feed is introduced into the column and purified to purity larger than the desired value. The resulting fractions are then blended with fresh feed to match the given… CONTINUE READING