Byelyankacin: A Novel Melanogenesis Inhibitor Produced by Enterobacter sp. B20

  title={Byelyankacin: A Novel Melanogenesis Inhibitor Produced by Enterobacter sp. B20},
  author={Senji Takahashi and Hiroki Iwai and Kunio Kosaka and Toshitsugu Miyazaki and Yuko Osanai and Nakako Arao and Kouichi Tanaka and Koji Nagai and Akira Nakagawa},
  journal={The Journal of Antibiotics},
A novel melanogenesis inhibitor, byelyankacin (1), was isolated from the fermentation broth of a bacterial strain. The producing organism, designated B20, was identified as a member of the genus Enterobacter based on taxonomic characteristics. 1 was obtained as a white powder from the culture medium by solvent extraction and serial chromatographic purification. The structure of 1 was determined as (E)-4-(2-isocyanovinyl)phenyl α-L-rhamnopyranoside on the basis of spectroscopic data. 1 potently… CONTINUE READING
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