By-passing of P-glycoprotein using immunoliposomes.


The over-expression of MDR1 P-glycoprotein has been associated with the development of multidrug-resistance in cancer cells. Methods used to overcome multidrug-resistance often involve the co-administration of inhibitors of P-glycoprotein. Here, we test the hypothesis that an immunoliposome-based drug delivery system may be used as an alternative approach… (More)


Cite this paper

@article{Huwyler2002BypassingOP, title={By-passing of P-glycoprotein using immunoliposomes.}, author={J{\"{o}rg Huwyler and Andrin Cerletti and Gert Fricker and Alex N. Eberle and Juergen Drewe}, journal={Journal of drug targeting}, year={2002}, volume={10 1}, pages={73-9} }