Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health?

PURPOSE OF REVIEW High-fiber diets have been shown to reduce plasma concentrations of inflammation markers. Increased production of fermentation-derived short-chain fatty acids (SCFAs) is one of the factors that could exert these positive effects. This review examines the effects of SCFAs on immune cells and discusses the relevance of their effects on… (More)