Butyrate-Induced Transcriptional Changes in Human Colonic Mucosa

Abstract

BACKGROUND Fermentation of dietary fiber in the colon results in the production of short chain fatty acids (mainly propionate, butyrate and acetate). Butyrate modulates a wide range of processes, but its mechanism of action is mostly unknown. This study aimed to determine the effects of butyrate on the transcriptional regulation of human colonic mucosa in… (More)
DOI: 10.1371/journal.pone.0006759

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