Busulfan induces oxidative stress-and Bcl-2 family gene-related apoptosis in epididymal sperm and testis of adult male mice

@inproceedings{Nasimi2016BusulfanIO,
  title={Busulfan induces oxidative stress-and Bcl-2 family gene-related apoptosis in epididymal sperm and testis of adult male mice},
  author={Parva Nasimi and Mohammad Reza Tabandeh and A. I. Sayma M. Vahdati and Saeed Khatamsaz},
  year={2016}
}
Introduction: Busulfan as a chemotherapeutic agent causes testicular germinal epithelium depletion and cytotoxicity in germ cells. The aim of this study was to assess antioxidant status, reactive oxygen species (ROS) generation and apoptosis-related genetic markers of adult male mouse sperm following busulfan treatment. Materials and Methods: Forty adult… CONTINUE READING