Buspirone treatment of cannabis dependence: A randomized, placebo-controlled trial.

@article{McRaeClark2015BuspironeTO,
  title={Buspirone treatment of cannabis dependence: A randomized, placebo-controlled trial.},
  author={A. McRae-Clark and N. Baker and K. Gray and T. Killeen and A. Wagner and K. Brady and C. L. DeVane and Jessica Norton},
  journal={Drug and alcohol dependence},
  year={2015},
  volume={156},
  pages={
          29-37
        }
}
  • A. McRae-Clark, N. Baker, +5 authors Jessica Norton
  • Published 2015
  • Medicine
  • Drug and alcohol dependence
  • BACKGROUND The purpose of this study was to evaluate the efficacy of buspirone, a partial 5-HT1A agonist, for treatment of cannabis dependence. METHODS One hundred seventy-five cannabis-dependent adults were randomized to receive either up to 60mg/day of buspirone (n=88) or placebo (n=87) for 12 weeks combined with a brief motivational enhancement therapy intervention and contingency management to encourage study retention. Cannabis use outcomes were assessed via weekly urine cannabinoid… CONTINUE READING
    34 Citations

    Topics from this paper

    Vilazodone for cannabis dependence: A randomized, controlled pilot trial.
    • 16
    Pharmacotherapies for cannabis dependence.
    • 45
    Quetiapine treatment for cannabis use disorder.
    Pharmacotherapy for the Treatment of Cannabis Use Disorder
    • 2
    Evidence-based Treatment Options in Cannabis Dependency.
    • 13
    Buspirone: Back to the Future.
    • R. Howland
    • Medicine
    • Journal of psychosocial nursing and mental health services
    • 2015
    • 22
    A Narrative Review of Psychological Cannabis Use Treatments with And Without Pharmaceutical Adjunct.
    • 6
    • PDF

    References

    SHOWING 1-10 OF 49 REFERENCES
    A placebo-controlled trial of buspirone for the treatment of marijuana dependence.
    • 58
    A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents.
    • 163
    • PDF
    A preliminary trial: double-blind comparison of nefazodone, bupropion-SR, and placebo in the treatment of cannabis dependence.
    • 69
    Treatment of cannabis dependence using escitalopram in combination with cognitive-behavior therapy: a double-blind placebo-controlled study
    • 33
    Pharmacotherapies for cannabis dependence.
    • 45
    Pharmacotherapy for Cannabis Dependence
    • 73
    Treatment of cannabis use disorders: a review of the literature.
    • 118