Buspirone treatment of cannabis dependence: A randomized, placebo-controlled trial.
@article{McRaeClark2015BuspironeTO, title={Buspirone treatment of cannabis dependence: A randomized, placebo-controlled trial.}, author={A. McRae-Clark and N. Baker and K. Gray and T. Killeen and A. Wagner and K. Brady and C. L. DeVane and Jessica Norton}, journal={Drug and alcohol dependence}, year={2015}, volume={156}, pages={ 29-37 } }
BACKGROUND
The purpose of this study was to evaluate the efficacy of buspirone, a partial 5-HT1A agonist, for treatment of cannabis dependence.
METHODS
One hundred seventy-five cannabis-dependent adults were randomized to receive either up to 60mg/day of buspirone (n=88) or placebo (n=87) for 12 weeks combined with a brief motivational enhancement therapy intervention and contingency management to encourage study retention. Cannabis use outcomes were assessed via weekly urine cannabinoid… CONTINUE READING
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