Buspirone maintenance does not alter the reinforcing, subjective, and cardiovascular effects of intranasal methamphetamine.

@article{Reynolds2017BuspironeMD,
  title={Buspirone maintenance does not alter the reinforcing, subjective, and cardiovascular effects of intranasal methamphetamine.},
  author={Anna R. Reynolds and Justin C Strickland and William W Stoops and Joshua A. Lile and Craig R Rush},
  journal={Drug and alcohol dependence},
  year={2017},
  volume={181},
  pages={25-29}
}
BACKGROUND Medications development efforts for methamphetamine-use disorder have targeted central monoamines because these systems are directly involved in the effects of methamphetamine. Buspirone is a dopamine autoreceptor and D3 receptor antagonist and partial agonist at serotonin 1A receptors, making it a logical candidate medication for methamphetamine… CONTINUE READING