Buruli ulcer.

  title={Buruli ulcer.},
  author={Thorbjorg Einarsdottir and Kris Huygen},
  journal={Human vaccines},
  volume={7 11},
Buruli Ulcer (BU) is a neglected, necrotizing skin disease, caused by M. ulcerans, that can leave patients with prominent scars and lifelong disability. M. ulcerans produces a diffusible lipid toxin, mycolactone, essential for bacterial virulence. Prevention is difficult as little is known about disease transmission and there is no vaccine. There have been several recent advances in the field. These include sequencing of the bacterial genome and of the giant plasmid responsible for mycolactone… CONTINUE READING
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