Burkitt's lymphoma: The Rosetta Stone deciphering Epstein-Barr virus biology

  title={Burkitt's lymphoma: The Rosetta Stone deciphering Epstein-Barr virus biology},
  author={Martin Rowe and Gemma L. Kelly and Andrew I Bell and Alan B. Rickinson},
  booktitle={Seminars in cancer biology},
Epstein-Barr virus was originally identified in the tumour cells of a Burkitt's lymphoma, and was the first virus to be associated with the pathogenesis of a human cancer. Studies on the relationship of EBV with Burkitt's lymphoma have revealed important general principles that are relevant to other virus-associated cancers. In addition, the impact of such studies on the knowledge of EBV biology has been enormous. Here, we review some of the key historical observations arising from studies on… CONTINUE READING

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