Burkholderia pseudomallei virulence: definition, stability and association with clonality.

@article{Ulett2001BurkholderiaPV,
  title={Burkholderia pseudomallei virulence: definition, stability and association with clonality.},
  author={Glen C Ulett and Bart J Currie and Timothy Clair and Michael Mayo and Natkunam Ketheesan and Justin T Labrooy and Daniel Gal and Robert Norton and Carol Anne Smith and Janice E. Barnes and Jon A. Warner and Robert G. Hirst},
  journal={Microbes and infection},
  year={2001},
  volume={3 8},
  pages={
          621-31
        }
}
Clinical presentations of melioidosis, caused by Burkholderia pseudomallei are protean, but the mechanisms underlying development of the different forms of disease remain poorly understood. In murine melioidosis, the level of virulence of B. pseudomallei is important in disease pathogenesis and progression. In this study, we used B. pseudomallei-susceptible BALB/c mice to determine the virulence of a library of clinical and environmental B. pseudomallei isolates from Australia and Papua New… CONTINUE READING

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