Burkholderia pseudomallei RpoS regulates OxyR and the katG-dpsA operon under conditions of oxidative stress.

@article{Jangiam2010BurkholderiaPR,
  title={Burkholderia pseudomallei RpoS regulates OxyR and the katG-dpsA operon under conditions of oxidative stress.},
  author={Witawat Jangiam and Suvit Loprasert and Duncan R Smith and Sumalee Tungpradabkul},
  journal={Microbiology and immunology},
  year={2010},
  volume={54 7},
  pages={
          389-97
        }
}
Burkholderia pseudomallei, the causative agent of the potentially fatal tropical disease melioidosis, is known to be highly resistant to oxidative stress although the mechanism of this resistance remains to be fully elucidated. Previous studies have shown that an OxyR is involved in the regulation of oxidative stress via the katG and dpsA genes encoding KatG and DpsA and that the alternative sigma factor, RpoS, plays a critical role in resistance to oxidative stress by regulating katG and katE… CONTINUE READING