Burkholderia cepacia complex: epithelial cell-pathogen confrontations and potential for therapeutic intervention.

@article{McClean2009BurkholderiaCC,
  title={Burkholderia cepacia complex: epithelial cell-pathogen confrontations and potential for therapeutic intervention.},
  author={Siobh{\'a}n McClean and M{\'a}ire Callaghan},
  journal={Journal of medical microbiology},
  year={2009},
  volume={58 Pt 1},
  pages={1-12}
}
Burkholderia cepacia complex (Bcc) is an important and virulent pathogen in cystic fibrosis patients. The interactions between this pathogen and the host lung epithelium are being widely investigated but remain to be elucidated. The complex is very versatile and its interactions with the lung epithelial cells are many and varied. The first steps in the interaction are penetration of the mucosal blanket and subsequent adherence to the epithelial cell surface. A range of epithelial receptors have… CONTINUE READING