Burkholderia cenocepacia phenotypic clonal variation during a 3.5-year colonization in the lungs of a cystic fibrosis patient.

@article{Coutinho2011BurkholderiaCP,
  title={Burkholderia cenocepacia phenotypic clonal variation during a 3.5-year colonization in the lungs of a cystic fibrosis patient.},
  author={Carla Patr{\'i}cia Coutinho and Carla C. C. R. de Carvalho and Andreia Madeira and Ana Pinto-de-Oliveira and Isabel S{\'a}-Correia},
  journal={Infection and immunity},
  year={2011},
  volume={79 7},
  pages={2950-60}
}
Chronic lung infection is the major cause of morbidity and premature mortality in cystic fibrosis (CF) patients. Bacteria of the Burkholderia cepacia complex are the most threatening pathogens in CF, and a better understanding of how these bacteria adapt to the CF airway environment and resist the host defense mechanisms and therapeutically administered antibiotics is crucial. To provide clues to the adaptive strategies adopted by Burkholderia cenocepacia during long-term colonization, we… CONTINUE READING

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