Burkholderia cenocepacia lipopolysaccharide, lipid A, and proinflammatory activity.

@article{Soyza2004BurkholderiaCL,
  title={Burkholderia cenocepacia lipopolysaccharide, lipid A, and proinflammatory activity.},
  author={Anthony De Soyza and Charles D. Ellis and C. M. Anjam Khan and Paul A. Corris and Raquel Demarco de Hormaeche},
  journal={American journal of respiratory and critical care medicine},
  year={2004},
  volume={170 1},
  pages={70-7}
}
Organisms from the Burkholderia cepacia complex are important pathogens in cystic fibrosis and are associated with increased rates of sepsis and death. These organisms comprise nine closely related species known as genomovars. B. cenocepacia (genomovar III) is the most prevalent and appears the most virulent. We investigated the biological activity of a reference panel of strains using whole-cell lysates to induce septic-shock related cytokines from differentiated human monocytic cells. We… CONTINUE READING
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