Burden of Invasive Group B Streptococcus Disease and Early Neurological Sequelae in South African Infants

@inproceedings{Dangor2015BurdenOI,
  title={Burden of Invasive Group B Streptococcus Disease and Early Neurological Sequelae in South African Infants},
  author={Ziyaad Dangor and Sanjay Govind Lala and Clare Louise Cutland and Anthonet Koen and Lisa Jose and Firdose Nakwa and Tanusha Ramdin and Joy Fredericks and Jeannette Wadula and Shabir A Madhi},
  booktitle={PloS one},
  year={2015}
}
INTRODUCTION Group B Streptococcus (GBS) is a leading cause of neonatal sepsis and meningitis. We aimed to evaluate the burden of invasive early-onset (0-6 days of life, EOD) and late-onset (7-89 days, LOD) GBS disease and subsequent neurological sequelae in infants from a setting with a high prevalence (29.5%) of HIV among pregnant women. METHODS A case-control study was undertaken at three secondary-tertiary care public hospitals in Johannesburg. Invasive cases in infants <3 months age were… CONTINUE READING
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