Bupropion hydrochloride versus placebo, in combination with cognitive behavioral therapy, for the treatment of cocaine abuse/dependence.

@article{Shoptaw2008BupropionHV,
  title={Bupropion hydrochloride versus placebo, in combination with cognitive behavioral therapy, for the treatment of cocaine abuse/dependence.},
  author={Steven Shoptaw and Keith Gregory Heinzerling and Erin J Rotheram-Fuller and Uyen H Kao and Pin-Chieh Wang and Michelle Anne Bholat and W Emily Ling},
  journal={Journal of addictive diseases},
  year={2008},
  volume={27 1},
  pages={
          13-23
        }
}
Bupropion hydrochloride is a dopamine and norepinephrine reuptake inhibitor which may be an effective treatment for cocaine dependence due to its ability to reverse deficits in dopaminergic functioning that occur in chronic cocaine users. We performed a randomized, double-blind, placebo controlled trial comparing outpatient treatment with bupropion (N = 37) and placebo (N = 33) in combination with standard cognitive behavioral therapy. There were no statistically significant differences between… CONTINUE READING

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