Buprenorphine treatment of opioid dependence: clinical trial of daily versus alternate-day dosing.

@article{Johnson1995BuprenorphineTO,
  title={Buprenorphine treatment of opioid dependence: clinical trial of daily versus alternate-day dosing.},
  author={Rolley E. Johnson and Thomas E Eissenberg and Maxine L. Stitzer and Eric C. Strain and Ira A. Liebson and George E. Bigelow},
  journal={Drug and alcohol dependence},
  year={1995},
  volume={40 1},
  pages={27-35}
}
Buprenorphine, a mu-opioid partial agonist, has demonstrated efficacy for the treatment of opioid dependence comparable to that of methadone. The clinical utility of buprenorphine would be enhanced if it could be dosed on a less than daily basis. The current study is a parallel-group outpatient clinical trial of daily versus alternate-day dosing with 8 mg… CONTINUE READING