Buprenorphine/Naloxone
@article{Orman2012BuprenorphineNaloxone, title={Buprenorphine/Naloxone}, author={Jennifer S. Orman and G. Keating}, journal={Drugs}, year={2012}, volume={69}, pages={577-607} }
SummaryAbstractBuprenorphine/naloxone (Suboxone®) comprises the partial μ-opioid receptor agonist buprenorphine in combination with the opioid antagonist naloxone in a 4: 1 ratio. When buprenorphine/naloxone is taken sublingually as prescribed, the naloxone exerts no clinically significant effect, leaving the opioid agonist effects of buprenorphine to predominate. However, when buprenorphine/naloxone is parenterally administered in patients physically dependent on full agonist opioids, the… CONTINUE READING
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