Bupivacaine injection of eye muscles to treat strabismus

@article{Scott2007BupivacaineIO,
  title={Bupivacaine injection of eye muscles to treat strabismus},
  author={Alan B. Scott and Danielle E Alexander and Joel Miller},
  journal={British Journal of Ophthalmology},
  year={2007},
  volume={91},
  pages={146 - 148}
}
Background: Bupivacaine injected into animal muscles induces a cycle of myotoxicity, degeneration, regeneration and hypertrophy of muscle fibres, without adverse effects on other tissues. This induced hypertrophy can be harnessed to treat strabismus. Methods: Bupivacaine, 4.5 ml of a 0.75% solution, was injected into the right lateral rectus (RLR) muscle of a patient who had diplopia and who showed 14-prism-dioptres oesotropia. Results: RLR paresis persisted for 7 days. Then, the RLR regained… Expand
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TLDR
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Histological changes underlying bupivacaine's effect on extra ocular muscle
TLDR
Extraocular muscle showed increased slow myosin proportion in bupivacaine injected muscles, and Muscle adaptation in untreated EOM was found with increased CSA, to clarify the clinical effects of BUP in extraocular muscle. Expand
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TLDR
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TLDR
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