Bupivacaine extended-release liposome injection for prolonged postsurgical analgesia in patients undergoing hemorrhoidectomy: a multicenter, randomized, double-blind, placebo-controlled trial.

@article{Gorfine2011BupivacaineEL,
  title={Bupivacaine extended-release liposome injection for prolonged postsurgical analgesia in patients undergoing hemorrhoidectomy: a multicenter, randomized, double-blind, placebo-controlled trial.},
  author={Stephen R. Gorfine and Erol Onel and Gary Patou and Zoran V. Krivokapi{\'c}},
  journal={Diseases of the colon and rectum},
  year={2011},
  volume={54 12},
  pages={1552-9}
}
BACKGROUND Bupivacaine extended-release liposome injection is a novel formulation of bupivacaine designed to achieve long-acting postoperative analgesia. OBJECTIVE The aim of this study was to compare the magnitude and duration of postoperative analgesia from a single dose of bupivacaine extended-release injection with placebo administered intraoperatively in patients undergoing hemorrhoidectomy. DESIGN This evaluation was a multicenter, randomized, double-blind, parallel-group, placebo… CONTINUE READING
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