Bullous SLE: response to methotrexate and relationship with disease activity.

  title={Bullous SLE: response to methotrexate and relationship with disease activity.},
  author={Giuseppe Malcangi and Giuliano Brandozzi and Mirella Giangiacomi and Maurizio Zampetti and Maria Giovanna Danieli},
  volume={12 1},
We report on a case of 40-year-old female with systemic lupus erythematosus (SLE) who developed a severe bullous eruption on sun-exposed areas. The bullous manifestation was associated with a flare of lupus serologies, whereas the previous manifestations of the disease were quiescent. Due to prior intolerance to many drugs, she was given oral methotrexate (10 mg/week). The drug administration was followed by a rapid and full resolution of cutaneous lesions. Five months later she developed a… CONTINUE READING

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