Building the Microtubule Cytoskeleton Piece by Piece*

  title={Building the Microtubule Cytoskeleton Piece by Piece*},
  author={Raymundo Alfaro-Aco and Sabine Petry},
  journal={The Journal of Biological Chemistry},
  pages={17154 - 17162}
The microtubule (MT) cytoskeleton gives cells their shape, organizes the cellular interior, and segregates chromosomes. These functions rely on the precise arrangement of MTs, which is achieved by the coordinated action of MT-associated proteins (MAPs). We highlight the first and most important examples of how different MAP activities are combined in vitro to create an ensemble function that exceeds the simple addition of their individual activities, and how the Xenopus laevis egg extract… 

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