Building mitotic chromosomes

@inproceedings{Ohta2011BuildingMC,
  title={Building mitotic chromosomes},
  author={Shinya Ohta and Laura A Wood and Jimi-Carlo Bukowski-Wills and Juri Rappsilber and William C Earnshaw},
  booktitle={Current opinion in cell biology},
  year={2011}
}
Mitotic chromosomes are the iconic structures into which the genome is packaged to ensure its accurate segregation during mitosis. Although they have appeared on countless journal cover illustrations, there remains no consensus on how the chromatin fiber is packaged during mitosis. In fact, work in recent years has both added to existing controversies and sparked new ones. By contrast, there has been very significant progress in determining the protein composition of isolated mitotic… CONTINUE READING
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