Building drug delivery into tissue engineering design

@article{Saltzman2002BuildingDD,
  title={Building drug delivery into tissue engineering design},
  author={W. Mark Saltzman and William L. Olbricht},
  journal={Nature Reviews Drug Discovery},
  year={2002},
  volume={1},
  pages={177-186}
}
The creation of efficient methods for manufacturing biotechnology drugs — many of which influence fundamental but complex cell behaviours, such as proliferation, migration and differentiation — is creating new opportunities for tissue repair. Many agents are potent and multifunctional; that is, they produce different effects within different tissues. Therefore, control of tissue concentration and spatial localization of delivery is essential for safety and effectiveness. Synthetic systems that… CONTINUE READING

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