Building blood vessels—stem cell models in vascular biology

  title={Building blood vessels—stem cell models in vascular biology},
  author={Lars Jakobsson and Johan Kreuger and Lena Claesson-Welsh},
  journal={The Journal of Cell Biology},
  pages={751 - 755}
Spheroids of differentiating embryonic stem cells, denoted embryoid bodies, constitute a high-quality model for vascular development, particularly well suited for loss-of-function analysis of genes required for early embryogenesis. This review examines vasculogenesis and angiogenesis in murine embryoid bodies and discusses the promise of stem cell-based models for the study of human vascular development. 
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  • Stem Cells .
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