Building a Three-Dimensional Nano-Bio Interface for Aptasensing: An Analytical Methodology Based on Steric Hindrance Initiated Signal Amplification Effect.

@article{Du2016BuildingAT,
  title={Building a Three-Dimensional Nano-Bio Interface for Aptasensing: An Analytical Methodology Based on Steric Hindrance Initiated Signal Amplification Effect.},
  author={Xiaojiao Du and Ding Guo Jiang and Nan Hao and Jing Qian and Liming Dai and Lei Zhou and Jianping Hu and Kun Wang},
  journal={Analytical chemistry},
  year={2016},
  volume={88 19},
  pages={
          9622-9629
        }
}
The development of novel detection methodologies in electrochemiluminescence (ECL) aptasensor fields with simplicity and ultrasensitivity is essential for constructing biosensing architectures. Herein, a facile, specific, and sensitive methodology was developed unprecedentedly for quantitative detection of microcystin-LR (MC-LR) based on three-dimensional boron and nitrogen codoped graphene hydrogels (BN-GHs) assisted steric hindrance amplifying effect between the aptamer and target analytes… CONTINUE READING