Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.

@article{Xie2011BufalinIA,
  title={Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.},
  author={Chuan-Ming Xie and Wood-yee Chan and Sidney Siubun Yu and Jun Zhao and Christopher H. K. Cheng},
  journal={Free radical biology & medicine},
  year={2011},
  volume={51 7},
  pages={1365-75}
}
Colorectal cancer is the second most common cause of cancer death in the world and about half of the patients with colorectal cancer require adjuvant therapy after surgical resection. Therefore, the eradication of cancer cells via chemotherapy constitutes a viable approach to treating patients with colorectal cancer. In this study, the effects of bufalin… CONTINUE READING