Bufadienolides and anti-angiogenic homoisoflavonoids from Rhodocodon cryptopodus, Rhodocodon rotundus and Rhodocodon cyathiformis.

@article{Whitmore2020BufadienolidesAA,
  title={Bufadienolides and anti-angiogenic homoisoflavonoids from Rhodocodon cryptopodus, Rhodocodon rotundus and Rhodocodon cyathiformis.},
  author={H. Whitmore and Kamakshi Sishtla and W. Knirsch and Jacky Andriantiana and S. Schwikkard and Eduard Mas-Claret and Sarah M Nassief and Sani M. Isyaka and T. Corson and D. Mulholland},
  journal={Fitoterapia},
  year={2020},
  pages={
          104479
        }
}
BACKGROUND Homoisoflavonoids have been shown to have potent anti-proliferative activities in endothelial cells over other cell types and have demonstrated a strong antiangiogenic potential in vitro and in vivo in animal models of ocular neovascularization. Three species of Rhodocodon (Scilloideaea subfamily of the Asparagaceae family), endemic to Madagascar, R. cryptopodus, R. rotundus and R. cyathiformis, were investigated. PURPOSE To isolate and test homoisoflavonoids for their… Expand
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